Protein Modification Reagents
AdipoGen Guanidine thiocyanate
Chemical. CAS 593-84-0. Formula CH5N3 . CHNS. MW 59.07 . 59.09. Guanidine thiocyanate is a powerful, chaotropic agent which is widely used for purification of proteins and nucleic acids. Guanidine thiocyanate is preferred for the purification of RNA because it dissociates the RNA into its nucleic acids and protein forms and is commonly used in the guanidinium thiocyanate-phenol-chloroform extraction method. As one of the strongest protein denaturants, it inactivates nucleases more than twice as fast as Guanidine hydrochloride. It is useful for denaturation and refolding of proteins. At high molarity solutions, Guanidine thiocyanate irreversibly inactivates RNase. Guanidine thiocyanate causes proteins to dissolve readily, thus disintegrating cellular structures.
Sigma Aldrich Fine Chemicals Biosciences Guanidine hydrochloride solution, 6M Reagent designed and manufactured under cGMP controls suitable for use in an IVD application | 500ML
Guanidine hydrochloride solution, 6M Reagent designed and manufactured under cGMP controls suitable for use in an IVD application | 500ML
Abcam Guanidine hydrochloride (6 M) Solution, 1000ML
MW 95.53 g/mol. Commonly used for denaturing proteins. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical PROTAC CRBN Degrader-1 1mg
A PROTAC that drives CRBN degradation (DC50 = 200 nM in HeLa cells)
Medchemexpress LLC DSPE-N3 | 2839508-98-2 | 96.4% | 831.11 g·mol⁻¹ | C43H83N4O9P | 25 MG
DSPE-N3 is an azide-functionalized phospholipid used as a click-chemistry reagent in biochemical and nanotechnology research. It enables both copper-catalyzed and strain-promoted azide-alkyne cycloadditions for reliable conjugation of biomolecules, surface modification, and lipid nanoparticle functionalization.
- Azide-functionalized phospholipid enabling click chemistry conjugation.
- Compatible with CuAAC and SPAAC reaction conditions.
- Suitable for nanoparticle and surface functionalization applications.
- White to off-white solid with standard storage requirements.
- Soluble in DMSO with warming and sonication for formulation.
- High purity (~96.4%) appropriate for research use.
![eMolecules 1144106-65-9 | Bromo-PEG1-azide | Broadpharm194.032 | C4H8BrN3O | 95.000 | BrCCOCCN=[N+]=[N-] | 1g | 433947074](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC1691006.jpg-250.jpg)
eMolecules 1144106-65-9 | Bromo-PEG1-azide | Broadpharm194.032 | C4H8BrN3O | 95.000 | BrCCOCCN=[N+]=[N-] | 1g | 433947074
Bromo-PEG1-azide | Broadpharm | 1144106-65-9194.032 | C4H8BrN3O | 95.000 | BrCCOCCN=[N+]=[N-] | 1g | 433947074
![eMolecules 2639395-40-5 | PTAD-PEG4-Azide | Broadpharm539.546 | C22H33N7O9 | 95.000 | COc1cc(ccc1OCCNC(=O)CCOCCOCCOCCOCCN=[N+]=[N-])-n1c(=O)[nH][nH]c1=O | 250mg | 573896753](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183599.JPG-250.jpg)
eMolecules 2639395-40-5 | PTAD-PEG4-Azide | Broadpharm539.546 | C22H33N7O9 | 95.000 | COc1cc(ccc1OCCNC(=O)CCOCCOCCOCCOCCN=[N+]=[N-])-n1c(=O)[nH][nH]c1=O | 250mg | 573896753
PTAD-PEG4-Azide | Broadpharm | 2639395-40-5539.546 | C22H33N7O9 | 95.000 | COc1cc(ccc1OCCNC(=O)CCOCCOCCOCCOCCN=[N+]=[N-])-n1c(=O)[nH][nH]c1=O | 250mg | 573896753
Medchemexpress LLC Dspe-peg4-dbco | 2112738-14-2 | MFCD30828684 | 95.0% | C71H116N3O15P | 10MG
DSPE-PEG4-DBCO is a lipid-polyethylene glycol conjugate bearing a dibenzocyclooctyne (DBCO) reactive group used for copper-free click chemistry and bioconjugation. It enables strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-functionalized partners, facilitating liposome functionalization, surface modification, and linker assembly in aqueous and physiological conditions.
- Provides a DBCO reactive handle for copper-free SPAAC.
- Contains a PEG4 spacer for improved solubility and reduced steric hindrance.
- Includes a lipid anchor for incorporation into lipid bilayers and liposomes.
- Suitable for bioconjugation under physiological conditions.
- High purity for consistent reaction performance.
Medchemexpress LLC TCO-PEG2-amine | 2141981-87-3 | 97.0% | C15H28N2O4 | 100 MG
TCO-PEG2-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. These molecules consist of two distinct ligands connected by a linker, where one targets an E3 ubiquitin ligase and the other targets the protein of interest. PROTACs function by harnessing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- For research use only